Compile Data Set for Download or QSAR
Found 12 of ki for UniProtKB: P43681
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataKi:  0.0720nMAssay Description:Binding affinity against nicotinic acetylcholine receptor using [3H]epibatidine as radioligand in rat brain tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8ZD0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50137787(6-(6-Chloro-pyridin-3-yl)-8-aza-bicyclo[3.2.1]octa...)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Binding affinity against nicotinic acetylcholine receptor alpha2-beta4 using [3H]epibatidine as radioligand expressed in HEK293 cells or tsA cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8ZD0PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  129nMAssay Description:Binding affinity against nicotinic acetylcholine receptor alpha4-beta4 using [3H]epibatidine as radioligand expressed in HEK293 cells or tsA cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50006616(CHEMBL3235484)copy SMILEScopy InChI
Affinity DataKi:  251nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50006614(CHEMBL3235482)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z3215RPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50400739(CHEMBL2203550)copy SMILEScopy InChI
Affinity DataKi:  5.58E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66WSPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50435344(CHEMBL2391541)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474C7GPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474C7GPubMed