Compile Data Set for Download or QSAR
Found 11 of ki for UniProtKB: P12497
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50422052(CHEMBL109952 | L-700417)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50067593(CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)copy SMILEScopy InChI
Affinity DataKi:  1.70nM IC50: 6nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21XCPubMedMMDB
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462131(CHEMBL2182010)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of HIV proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QTKPubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)copy SMILEScopy InChI
Affinity DataKi:  4nM IC50: 13nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)copy SMILEScopy InChI
Affinity DataKi:  9.70nM IC50: 17nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)copy SMILEScopy InChI
Affinity DataKi:  10nM IC50: 19nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21XCPubMedMMDB
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)copy SMILEScopy InChI
Affinity DataKi:  13nM IC50: 24nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)copy SMILEScopy InChI
Affinity DataKi:  22nM IC50: 39nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21XCPubMedMMDB
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)copy SMILEScopy InChI
Affinity DataKi:  27nM IC50: 46nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N21XCPubMedMMDB
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
CSIR-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)copy SMILEScopy InChI
Affinity DataKi:  30nM IC50: 52nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair