Compile Data Set for Download or QSAR
Found 23 of ki for UniProtKB: P09884
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225280(CHEMBL3144215)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KMTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293303(CHEMBL498103 | gallic acid 5,6-dihydroxy-3-carboxy...)copy SMILEScopy InChI
Affinity DataKi:  830nMAssay Description:Inhibition of DNA polymerase alpha from human KB3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZC7PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025592((4-Butyl-phenyl)-(6-methylsulfanyl-9H-purin-2-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025600((4-Butyl-phenyl)-(6-methoxy-9H-purin-2-yl)-amine |...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025598((4-Butyl-phenyl)-(6-chloro-9H-purin-2-yl)-amine | ...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153106(CHEMBL189703 | [(3S,10R,13R,17R)-17-((R)-1,5-Dimet...)copy SMILEScopy InChI
Affinity DataKi:  3.75E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025597((4-Butyl-phenyl)-(9H-purin-2-yl)-amine | CHEMBL278...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)copy SMILEScopy InChI
Affinity DataKi:  7.50E+3nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KMTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)copy SMILEScopy InChI
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153113(CHEMBL364611 | [(3S,10R,13R,17R)-17-((E)-(1R,4S)-4...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013074(2-(4-Butyl-phenylamino)-1,9-dihydro-purin-6-one | ...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)copy SMILEScopy InChI
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025593(CHEMBL16122 | N*2*-(4-Butyl-phenyl)-9H-purine-2,6-...)copy SMILEScopy InChI
Affinity DataKi:  1.44E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153106(CHEMBL189703 | [(3S,10R,13R,17R)-17-((R)-1,5-Dimet...)copy SMILEScopy InChI
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405103(CHEMBL2115349)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KMTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50153113(CHEMBL364611 | [(3S,10R,13R,17R)-17-((E)-(1R,4S)-4...)copy SMILEScopy InChI
Affinity DataKi:  2.79E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37BHPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025595(2-(4-Butyl-phenylamino)-1,9-dihydro-purine-6-thion...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405103(CHEMBL2115349)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KMTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405103(CHEMBL2115349)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KMTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013075(2-(Indan-5-ylamino)-1,9-dihydro-purin-6-one | CHEM...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+4nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50118823(2,2-Dimethyl-propionic acid [5-(7-amino-[1,2,3]tri...)copy SMILEScopy InChI
Affinity DataKi:  1.56E+5nMAssay Description:Ability to inhibit the incorporation of dATP into DNA by DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6QWFPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50118822(2,2-Dimethyl-propionic acid [5-(6-amino-8-bromo-pu...)copy SMILEScopy InChI
Affinity DataKi:  5.48E+5nMAssay Description:Ability to inhibit the incorporation of dATP into DNA by DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6QWFPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013093(2-(3-Ethyl-4-methyl-phenylamino)-1,9-dihydro-purin...)copy SMILEScopy InChI
Affinity DataKi:  1.76E+6nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6R83PubMed