Compile Data Set for Download or QSAR
Found 4 of ki for UniProtKB: P06240
LigandPNGBDBM25191(4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-y...)copy SMILEScopy InChI
Affinity DataKi:  20nM ΔG°:  -10.4kcal/mole IC50: 59nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP80G3PubMed
LigandPNGBDBM25979(BMCL18324 Compound 1 | N-[4-methoxy-3-(4-methylpip...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nM ΔG°:  -7.49kcal/mole IC50: 8.40E+3nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP80G3PubMed
LigandPNGBDBM25980(BMCL18324 Compound 3 | CHEMBL270164 | N-(3-cyanoph...)copy SMILEScopy InChI
Affinity DataKi: >5.40E+3nM ΔG°: >-7.11kcal/mole IC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP80G3PubMed
LigandPNGBDBM25981(BMCL18324 Compound 17 | CHEMBL273158 | D3RKN_78 | ...)copy SMILEScopy InChI
Affinity DataKi: >5.40E+3nM ΔG°: >-7.11kcal/mole IC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP80G3PubMed