Compile Data Set for Download or QSAR
Found 346 of ki for UniProtKB: P25779
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50229129(4-Methyl-piperazine-1-carboxylic acid [(S)-1-((E)-...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Time dependent inhibition of Trypanosoma cruzi cruzain using Cbz-Phe-Arg-AMC as substrate assessed as inhibition constant for EI complex measured for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RC5PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50286450(CHEMBL128135 | [(S)-1-((S)-1-Benzyl-2-oxo-ethylcar...)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Time dependent inhibition of Trypanosoma cruzi cruzain using Cbz-Phe-Arg-AMC as substrate assessed as inhibition constant for EI complex measured for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RC5PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50201259(CHEMBL3907022)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32XR1PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50581372(CHEMBL5079418)copy SMILES
Affinity DataKi:  0.5nMAssay Description:Time dependent inhibition of Trypanosoma cruzi cruzain using Cbz-Phe-Arg-AMC as substrate assessed as inhibition constant for EI complex measured for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RC5PubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502827(CHEMBL4565840)copy SMILEScopy InChI
Affinity DataKi:  0.631nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34WRPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108858(CHEMBL347459 | {1-[2-Oxo-1-phenethyl-3-(3-phenyl-p...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108858(CHEMBL347459 | {1-[2-Oxo-1-phenethyl-3-(3-phenyl-p...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108849(CHEMBL321974 | {(S)-3-Methyl-1-[(S)-2-oxo-1-phenet...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Affinity for cysteine protease (Cruzipain) of Chagas' diseaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37VPPPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108849(CHEMBL321974 | {(S)-3-Methyl-1-[(S)-2-oxo-1-phenet...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108857(CHEMBL160000 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108857(CHEMBL160000 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108846(CHEMBL161038 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50451631(CHEMBL4212454)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1P7RPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50451625(CHEMBL4217414)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Covalent inhibition of Trypanosoma cruzi cruzipain using Z-Phe-Arg-7-amidomethylcoumarin as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5K9TPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502846(CHEMBL4451757)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34WRPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502833(CHEMBL4473385)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34WRPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50451631(CHEMBL4212454)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125W7DPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50451625(CHEMBL4217414)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125W7DPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50451625(CHEMBL4217414)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1P7RPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50304793((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-1-ox...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Covalent inhibition of Trypanosoma cruzi cruzipain using Z-Phe-Arg-7-amidomethylcoumarin as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5K9TPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Affinity for cysteine protease (Cruzipain) of Chagas' diseaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37VPPPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50304793((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-1-ox...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125W7DPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108862(CHEMBL161651 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108862(CHEMBL161651 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108840(3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108840(3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50514675(CHEMBL4472987)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as rate constant for enzyme-inhibitor-substrate complex using Cbz-Phe-Arg-AMC as substrate measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6PQDPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502822(CHEMBL4522247)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as inhibitor constant using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34WRPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108852(CHEMBL100849 | [(S)-1-((S)-1-Benzyl-2-oxo-3-phenet...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Affinity for cysteine protease (Cruzipain) of Chagas' diseaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37VPPPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108852(CHEMBL100849 | [(S)-1-((S)-1-Benzyl-2-oxo-3-phenet...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108852(CHEMBL100849 | [(S)-1-((S)-1-Benzyl-2-oxo-3-phenet...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108863(CHEMBL162695 | [1-(1-Benzyl-3-isopropylsulfanyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108863(CHEMBL162695 | [1-(1-Benzyl-3-isopropylsulfanyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108854(CHEMBL158806 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108874(CHEMBL351045 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  4.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108866((1-{1-Benzyl-3-[1-(2,2-dimethyl-propyl)-1,3,3-trim...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108866((1-{1-Benzyl-3-[1-(2,2-dimethyl-propyl)-1,3,3-trim...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108850(CHEMBL158567 | {1-[1-Benzyl-2-oxo-3-(3-phenyl-prop...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108873(CHEMBL161424 | [1-(1-Benzyl-3-sec-butylsulfanyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108873(CHEMBL161424 | [1-(1-Benzyl-3-sec-butylsulfanyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108841(CHEMBL161508 | [1-(1-Benzyl-3-cyclohexylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50108841(CHEMBL161508 | [1-(1-Benzyl-3-cyclohexylsulfanyl-2...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50375354(CHEMBL258808)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GPFPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50375354(CHEMBL258808)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5G0VPubMed
TargetCruzipain(Trypanosoma cruzi)TBA
LigandPNGBDBM50502832(CHEMBL4579894)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P34WRPubMed
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