BindingDB PrimarySearch

Found 2 of kd data for polymerid = 2712

Targets 88 ▿
- Androgen receptor 155
- Cytochrome P450 2D6 103
- Cytochrome P450 2C9 81
- Thromboxane-A synthase 76
- Cytochrome P450 3A4 68
- Prostaglandin E synthase 65
- Cytochrome P450 2C19 65
- Cytochrome P450 1A2 54
- Glycogen synthase kinase-3 beta 35
- Cannabinoid receptor 2 31
- Neuropeptide Y receptor type 5 29
- Prostacyclin receptor 29
- Aldo-keto reductase family 1 member C3 28
- Chitinase B 21
- Carboxylic ester hydrolase 16
- Cannabinoid receptor 1 16
- Acetylcholinesterase 16
- Chitinase A 10
- Chitinase C1 10
- ATP-dependent translocase ABCB1 10
- Prostaglandin E2 receptor EP4 subtype 7
- Aldo-keto reductase family 1 member C4 7
- Prostaglandin E2 receptor EP3 subtype 7
- Aldo-keto reductase family 1 member C2 7
- Aldo-keto reductase family 1 member C1 7
- Prostaglandin E2 receptor EP1 subtype 7
- Prostaglandin E2 receptor EP2 subtype 7
- Carbonyl reductase [NADPH] 1 7
- Prostaglandin F2-alpha receptor 5
- Prostaglandin D2 receptor 5
- Thromboxane A2 receptor 5
- Ubiquitin carboxyl-terminal hydrolase 5 4
- Prostaglandin G/H synthase 2 2
- Ubiquitin carboxyl-terminal hydrolase isozyme L1 2
- Glutamate receptor ionotropic, NMDA 1 2
- Solute carrier family 22 member 1 1
- Type-2 angiotensin II receptor 1
- Gamma-aminobutyric acid type B receptor subunit 1 1
- Solute carrier family 22 member 2 1
- Glycerophosphocholine phosphodiesterase GPCPD1 1
- Endothelin-1 receptor 1
- Muscarinic acetylcholine receptor M2 1
- Caspase-3 1
- Interleukin-1 beta 1
- Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) 1
- Platelet-derived growth factor subunit B 1
- Ubiquitin carboxyl-terminal hydrolase 14 1
- Beta-1 adrenergic receptor 1
- Glucocorticoid receptor 1
- D(2) dopamine receptor 1
- Nitric oxide synthase, endothelial 1
- Prostaglandin G/H synthase 1 1
- Phosphodiesterase 3a 1
- Lipopolysaccharide-induced tumor necrosis factor-alpha factor 1
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 1
- B2 bradykinin receptor 1
- Neuronal acetylcholine receptor subunit alpha-9 1
- Voltage-dependent T-type calcium channel subunit alpha-1H 1
- Type-1 angiotensin II receptor A 1
- Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1
- Ubiquitin carboxyl-terminal hydrolase 4 1
- 5-hydroxytryptamine receptor 2A 1
- D(1A) dopamine receptor 1
- Angiotensin-converting enzyme 1
- Polyamine deacetylase HDAC10 1
- Sigma non-opioid intracellular receptor 1 1
- Beta-arrestin-1 1
- Adenosine receptor A1 1
- Histamine H1 receptor 1
- Aldo-keto reductase family 1 member B1 [K65Q] 1
- 5-hydroxytryptamine receptor 1B 1
- Pro-neuropeptide Y 1
- Mu-type opioid receptor 1
- Vasoactive intestinal polypeptide receptor 1 1
- Leukotriene C4 synthase 1
- Nanos homolog 2 1
- Gamma-aminobutyric acid receptor subunit alpha-1 1
- Substance-P receptor 1
- Natriuretic peptides A 1
- Histone deacetylase 2 1
- Corticotropin-releasing factor receptor 1 1
- Histone deacetylase 1 1
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D 1
- Acidic mammalian chitinase 1
- Insulin receptor substrate 1 1
- Cholesterol side-chain cleavage enzyme, mitochondrial 1
- Cholecystokinin 1
- Adenosine receptor A2a 1
- ...
Publications 31 ▿
- J Med Chem 46: 5416-27 (2003) 132
- Bioorg Med Chem 21: 2868-78 (2013) 119
- Bioorg Med Chem Lett 27: 3733-3738 (2017) 86
- J Med Chem 63: 10396-10411 (2020) 66
- Bioorg Med Chem 15: 174-85 (2006) 61
- Bioorg Med Chem Lett 14: 333-6 (2003) 55
- Bioorg Med Chem Lett 19: 1807-10 (2009) 53
- Bioorg Med Chem Lett 25: 236-40 (2014) 51
- J Med Chem 24: 1139-48 (1982) 50
- J Pharmacol Exp Ther 314: 77-85 (2005) 46
- Bioorg Med Chem Lett 11: 2993-5 (2001) 43
- Bioorg Med Chem Lett 15: 3091-5 (2005) 34
- Bioorg Med Chem 20: 4901-14 (2012) 32
- Bioorg Med Chem Lett 17: 5573-6 (2007) 31
- Bioorg Med Chem 17: 2751-8 (2009) 30
- Bioorg Med Chem Lett 22: 2020-3 (2012) 29
- J Med Chem 24: 1149-55 (1982) 25
- Bioorg Med Chem Lett 22: 285-8 (2011) 22
- Bioorg Med Chem Lett 15: 3284-7 (2005) 17
- Bioorg Med Chem Lett 16: 4861-4 (2006) 14
- Bioorg Med Chem 21: 2068-78 (2013) 13
- Eur J Pharm Sci 16: 159-65 (2002) 10
- Bioorg Med Chem Lett 23: 4328-31 (2013) 9
- Bioorg Med Chem Lett 19: 2630-3 (2009) 8
- ACS Med Chem Lett 9: 884-888 (2018) 4
- Bioorg Med Chem Lett 15: 3279-83 (2005) 3
- Bioorg Med Chem 18: 5835-44 (2010) 3
- Bioorg Med Chem Lett 10: 2787-90 (2000) 2
- Bioorg Med Chem Lett 13: 4277-9 (2003) 2
- Bioorg Med Chem 17: 6270-8 (2009) 1
- Antimicrob Agents Chemother 53: 580-6 (2009) 1
Institutions 22 ▿
- [Dainippon Sumitomo Pharma. Co. Ltd] 141
- [Taisho Pharmaceutical Co, Ltd] 132
- [Taisho Pharmaceutical Co., Ltd] 101
- [Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aoba-ku, Yokohama 227-0033, Japan.] 86
- [TBA] 75
- [Fujisawa Pharmaceutical Co., Ltd.] 68
- [Gifu Pharmaceutical University] 66
- [Chugai Pharmaceutical Co., Ltd] 61
- [GSK] 53
- [RaQualia Pharma Inc] 51
- [Taisho Pharmaceutical Co., Ltd.] 43
- [Kitasato University] 42
- [Meiji Pharmaceutical University] 32
- [Chugai Pharmaceutical Co. Ltd.] 31
- [Shionogi& Co., Ltd] 29
- [Dainippon Sumitomo Pharma Co., Ltd] 13
- [Kyoto Pharmaceutical University] 10
- [Tokyo University of Agriculture] 9
- [Kansai University] 4
- [Fujisawa Pharmaceutical Co., Ltd, Fujisawa Pharmaceutical Co. Ltd] 2
- [Fujisawa Pharmaceutical Co., Ltd, Fujisawa Pharmaceutical Co. Ltd] 2
- [Kyushu University] 1
Affinity: 0.10 to 4.7E+5 nM▿
- Ki 108
- IC50 896
- Kd 1
- EC50 47
- Affinity ≤ nM
Xtal structures: 7
Docked structures: 0
Catalog Cmpds: 42