Compile Data Set for Download or QSAR
Found 3 of kd for UniProtKB: P35498
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505257(CHEMBL4471012)copy SMILEScopy InChI
Affinity DataKd:  140nMAssay Description:Binding affinity to human recombinant Nav1.1 by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM76858(US9546164, 580 | US9694002, 580)copy SMILEScopy InChI
Affinity DataKd:  140nMAssay Description:Binding affinity to human recombinant Nav1.1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90CZDPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
SiteOne Therapeutics

Curated by ChEMBL
LigandPNGBDBM50521571(CHEMBL4464990)copy SMILEScopy InChI
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of full length human Nav1.1 expressed in CHO cells at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed