Affinity DataKd: 0.200nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 0.200nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.590nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Inhibition of LCK in human HEK293 cells after 1 hr by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
Affinity DataKd: 5.30nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
Affinity DataKd: 5.80nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6.20nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Average Binding Constant for LCK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 20nMpH: 7.5Assay Description:In vitro activity assay using various kinases.More data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Binding affinity to human LCK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Dissociation constant for binding to SH2 domain of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity towards p56 Lck tyrosine kinase SH2 domain was determined by biological assayMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 44nMAssay Description:Average Binding Constant for LCK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 47nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 49nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Average Binding Constant for LCK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 62nMAssay Description:Average Binding Constant for LCK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 72nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataKd: 92nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged LCK expressed in baculovirus expression system using srctide as substrate inc...More data for this Ligand-Target Pair
Affinity DataKd: 94nMAssay Description:Binding affinity to recombinant human full length N-terminal GST-tagged LCK expressed in baculovirus expression system using srctide as substrate inc...More data for this Ligand-Target Pair
Affinity DataKd: 99nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 99nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Dissociation constant for p56 Lck tyrosine kinase SH2 domain binding to C-terminal ITAM2 phosphopeptideMore data for this Ligand-Target Pair
