Compile Data Set for Download or QSAR
Found 210 of kd for UniProtKB: P31749
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108433(US8609688, 11)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108434(US8609688, 12)copy SMILEScopy InChI
Affinity DataKd:  0.200nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108431(US8609688, 9)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108434(US8609688, 12)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108431(US8609688, 9)copy SMILEScopy InChI
Affinity DataKd:  0.200nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108432(US8609688, 10)copy SMILEScopy InChI
Affinity DataKd:  0.200nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108433(US8609688, 11)copy SMILEScopy InChI
Affinity DataKd:  0.200nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108432(US8609688, 10)copy SMILEScopy InChI
Affinity DataKd:  0.200nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataKd:  0.400nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataKd:  0.400nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)copy SMILEScopy InChI
Affinity DataKd:  0.640nMAssay Description:Binding affinity to wild-type human partial length AKT1 expressed in bacterial expression system assessed as residual binding level by Kinomescan met...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108427(US8609688, 5)copy SMILEScopy InChI
Affinity DataKd:  0.700nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108427(US8609688, 5)copy SMILEScopy InChI
Affinity DataKd:  0.700nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108440(US8609688, 18)copy SMILEScopy InChI
Affinity DataKd:  0.800nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108440(US8609688, 18)copy SMILEScopy InChI
Affinity DataKd:  0.800nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108437(US8609688, 15)copy SMILEScopy InChI
Affinity DataKd:  1.10nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108436(US8609688, 14)copy SMILEScopy InChI
Affinity DataKd:  1.10nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108436(US8609688, 14)copy SMILEScopy InChI
Affinity DataKd:  1.10nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108437(US8609688, 15)copy SMILEScopy InChI
Affinity DataKd:  1.10nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108430(US8609688, 8)copy SMILEScopy InChI
Affinity DataKd:  1.20nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108430(US8609688, 8)copy SMILEScopy InChI
Affinity DataKd:  1.20nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50586993(CHEMBL5091595)copy SMILES
Affinity DataKd:  1.30nMAssay Description:Binding affinity to wild-type human partial length AKT1 expressed in bacterial expression system assessed as residual binding level by Kinomescan met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0D73PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108428(US8609688, 6)copy SMILEScopy InChI
Affinity DataKd:  1.40nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108428(US8609688, 6)copy SMILEScopy InChI
Affinity DataKd:  1.40nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108435(US8609688, 13)copy SMILEScopy InChI
Affinity DataKd:  1.40nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108435(US8609688, 13)copy SMILEScopy InChI
Affinity DataKd:  1.40nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108438(US8609688, 16)copy SMILEScopy InChI
Affinity DataKd:  1.70nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108438(US8609688, 16)copy SMILEScopy InChI
Affinity DataKd:  1.70nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50586995(CHEMBL5082198)copy SMILES
Affinity DataKd:  1.80nMAssay Description:Binding affinity to wild-type human partial length AKT1 expressed in bacterial expression system assessed as residual binding level by Kinomescan met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0D73PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50586994(CHEMBL5073195)copy SMILES
Affinity DataKd:  1.90nMAssay Description:Binding affinity to wild-type human partial length AKT1 expressed in bacterial expression system assessed as residual binding level by Kinomescan met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0D73PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)copy SMILEScopy InChI
Affinity DataKd:  2.20nMAssay Description:Binding constant for AKT1 kinase domainMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108439(US8609688, 17)copy SMILEScopy InChI
Affinity DataKd:  3.10nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108439(US8609688, 17)copy SMILEScopy InChI
Affinity DataKd:  3.10nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50586992(CHEMBL5078362)copy SMILES
Affinity DataKd:  4nMAssay Description:Binding affinity to wild-type human partial length AKT1 expressed in bacterial expression system assessed as residual binding level by Kinomescan met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0D73PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50585740(CHEMBL5069422)copy SMILES
Affinity DataKd:  4.80nMAssay Description:Binding affinity to DNA-tagged AKT1 (unknown origin) assessed as dissociation constant by q-PCR based competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2N17PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50585742(CHEMBL5089002)copy SMILES
Affinity DataKd:  5.5nMAssay Description:Binding affinity to DNA-tagged AKT1 (unknown origin) assessed as dissociation constant by q-PCR based competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2N17PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108425(US8609688, 3)copy SMILEScopy InChI
Affinity DataKd:  7nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108425(US8609688, 3)copy SMILEScopy InChI
Affinity DataKd:  7nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108429(US8609688, 7)copy SMILEScopy InChI
Affinity DataKd:  7.10nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108429(US8609688, 7)copy SMILEScopy InChI
Affinity DataKd:  7.10nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  20nMAssay Description:Binding constant for AKT1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  20nMAssay Description:Binding constant for AKT1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50585739(CHEMBL5088272)copy SMILES
Affinity DataKd:  26nMAssay Description:Binding affinity to DNA-tagged AKT1 (unknown origin) assessed as dissociation constant by q-PCR based competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2N17PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50078211(CHEMBL3414684)copy SMILEScopy InChI
Affinity DataKd:  30nMAssay Description:Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FGXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108442(US8609688, 20)copy SMILEScopy InChI
Affinity DataKd:  57.3nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108442(US8609688, 20)copy SMILEScopy InChI
Affinity DataKd:  57.3nMpH: 7.5 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM431867(US10550114, Compound 1a)copy SMILEScopy InChI
Affinity DataKd:  58nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1N97US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM431868(US10550114, Compound 1b)copy SMILEScopy InChI
Affinity DataKd:  62nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM50313650(8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...)copy SMILEScopy InChI
Affinity DataKd:  69nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1N97US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM15138(5-indazolyl pyridine 11g | 5-{5-[(2S)-2-amino-3-ph...)copy SMILEScopy InChI
Affinity DataKd:  76nMAssay Description:Binding constant for AKT1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
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