Compile Data Set for Download or QSAR
Found 195 Enz. Inhib. hit(s) with all data for entry = 50035840
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089259(CHEMBL3577902)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257166(CHEMBL2325330)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089252(CHEMBL3577889)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089248(CHEMBL3577881)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257183(CHEMBL2324755)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Antagonist activity against human TRPM8 by single cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089256(CHEMBL3577905)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257215(CHEMBL2324411)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibition of rat NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089246(CHEMBL3577883)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257215(CHEMBL2324411)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:Inhibition of rat NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of human NaV1.6 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257169(CHEMBL2323074)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257165(CHEMBL2324391)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089254(CHEMBL3577907)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257182(CHEMBL2324753)copy SMILEScopy InChI
Affinity DataIC50: 199nMAssay Description:Inhibition of human NaV1.6 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089253(CHEMBL3577900)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257168(CHEMBL2325013)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257210(CHEMBL2324742)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257215(CHEMBL2324411)copy SMILEScopy InChI
Affinity DataIC50: 216nMAssay Description:Inhibition of human NaV1.1 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089255(CHEMBL3577906)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257217(CHEMBL2323100)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257179(CHEMBL2325622)copy SMILEScopy InChI
Affinity DataIC50: 264nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257182(CHEMBL2324753)copy SMILEScopy InChI
Affinity DataIC50: 276nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257168(CHEMBL2325013)copy SMILEScopy InChI
Affinity DataIC50: 279nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089262(CHEMBL3577898)copy SMILEScopy InChI
Affinity DataIC50: 288nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257215(CHEMBL2324411)copy SMILEScopy InChI
Affinity DataIC50: 292nMAssay Description:Inhibition of human NaV1.3 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 299nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089251(CHEMBL3576881)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257174(CHEMBL2323073)copy SMILEScopy InChI
Affinity DataIC50: 321nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257174(CHEMBL2323073)copy SMILEScopy InChI
Affinity DataIC50: 324nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257169(CHEMBL2323074)copy SMILEScopy InChI
Affinity DataIC50: 325nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089258(CHEMBL3577903)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089297(CHEMBL3577886)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 372nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257175(CHEMBL2324776)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257210(CHEMBL2324742)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257179(CHEMBL2325622)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089267(CHEMBL3577893)copy SMILEScopy InChI
Affinity DataIC50: 446nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257163(CHEMBL2322421)copy SMILEScopy InChI
Affinity DataIC50: 465nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257166(CHEMBL2325330)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257215(CHEMBL2324411)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of human NaV1.6 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257182(CHEMBL2324753)copy SMILEScopy InChI
Affinity DataIC50: 517nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257214(CHEMBL2325601)copy SMILEScopy InChI
Affinity DataIC50: 552nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257182(CHEMBL2324753)copy SMILEScopy InChI
Affinity DataIC50: 556nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257174(CHEMBL2323073)copy SMILEScopy InChI
Affinity DataIC50: 616nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257178(CHEMBL2325627)copy SMILEScopy InChI
Affinity DataIC50: 658nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 677nMAssay Description:Inhibition of human NaV1.1 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
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