Compile Data Set for Download or QSAR
Found 112 of ki data for polymerid = 10768,4753
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231742(2-(3,4-dihydro-1H-isoquinolin-2-yl)-7,7-dimethyl-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231736(2-butylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231740(2-benzyloxy-7,8-dihydro-6H-quinolin-5-one | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231735(2-(indan-2-ylamino)-7,7-dimethyl-5-oxo-5,6,7,8-tet...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438307(CHEMBL2408583)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231733(7,7-dimethyl-5-oxo-2-propylamino-5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231720(2-benzylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438310(CHEMBL2408581)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231738(7,7-dimethyl-2-pyridin-2-ylethynyl-7,8-dihydro-6H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231722(2-hexylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231730(2-cyclohexylamino-5-oxo-5,6,7,8-tetrahydroquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231756(2-cyclohexylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231751(6-phenylethynyl-nicotinic acid methyl ester | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438280(CHEMBL2408409)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+3nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231723(2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231760(2-(benzyl-methyl-amino)-7,7-dimethyl-5-oxo-5,6,7,8...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438296(CHEMBL2408567)copy SMILEScopy InChI
Affinity DataIC50: 6.16E+3nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231727(CHEMBL253348 | cid_2931812 | pyrazine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231731(2-azepanyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231746(2-[4-(4-methoxy-phenyl)-piperazin-1-yl]-7,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231724(3-chloro-2-cyclopentylamino-7,7-dimethyl-7,8-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231729(2-benzylamino-7,7-dimethyl-7,8-dihydro-6H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231739(2-(4-phenyl-piperazin-1-yl)-7,8-dihydro-6H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438302(CHEMBL2408562)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231732(7,7-dimethyl-3-nitro-2-(4-phenyl-3,6-dihydro-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50371237(CHEMBL1204390)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231765(2-(cyclopentylamino)-7,7-dimethyl-3-(2H-tetrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231766(2-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50371237(CHEMBL1204390)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231725(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231763(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Antagonist activity at rat mGluR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231745(2-(benzyl-methyl-amino)-5-oxo-5,6,7,8-tetrahydroqu...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231740(2-benzyloxy-7,8-dihydro-6H-quinolin-5-one | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231761(3-bromo-2-cyclopentylamino-7,7-dimethyl-7,8-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231762(2-benzylsulfanyl-5-oxo-5,6,7,8-tetrahydroquinoline...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231737(3-bromo-2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-7,7...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231726(2-(adamantan-1-ylamino)-7,7-dimethyl-5-oxo-5,6,7,8...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231729(2-benzylamino-7,7-dimethyl-7,8-dihydro-6H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231758(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231723(2-benzylsulfanyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231725(2-cyclopentylamino-7,7-dimethyl-5-oxo-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231721(2-pyridin-2-ylethynyl-7,8-dihydro-6H-quinolin-5-on...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438310(CHEMBL2408581)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+4nMAssay Description:Negative allosteric modulation of human mGluR1 expressed in CHO cells assessed as inhibition of L-glutamate-induced intracellular cAMP accumulation t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231745(2-(benzyl-methyl-amino)-5-oxo-5,6,7,8-tetrahydroqu...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Displacement of [3H]MPEP from rat mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04B2PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438308(CHEMBL1438160)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438306(CHEMBL2408584)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438297(CHEMBL2408566)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438285(CHEMBL2408578)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438284(CHEMBL2408580)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438282(CHEMBL2408407)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
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