Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 10833
TargetCaspase-8(Homo sapiens (Human))TBA
LigandPNGBDBM572147(US11447497, Example 4)copy SMILES
Affinity DataIC50: 1nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-1(Homo sapiens (Human))TBA
LigandPNGBDBM572147(US11447497, Example 4)copy SMILES
Affinity DataIC50: 2nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-1(Homo sapiens (Human))TBA
LigandPNGBDBM572145(US11447497, Example 2)copy SMILES
Affinity DataIC50: 4nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-1(Homo sapiens (Human))TBA
LigandPNGBDBM572144(US11447497, Example 1)copy SMILES
Affinity DataIC50: 9nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-8(Homo sapiens (Human))TBA
LigandPNGBDBM572145(US11447497, Example 2)copy SMILES
Affinity DataIC50: 28nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-3(Homo sapiens (Human))TBA
LigandPNGBDBM572145(US11447497, Example 2)copy SMILES
Affinity DataIC50: 32nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-9(Homo sapiens (Human))TBA
LigandPNGBDBM572145(US11447497, Example 2)copy SMILES
Affinity DataIC50: 38nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-1(Homo sapiens (Human))TBA
LigandPNGBDBM572146(US11447497, Example 3)copy SMILES
Affinity DataIC50: 65nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-9(Homo sapiens (Human))TBA
LigandPNGBDBM572147(US11447497, Example 4)copy SMILES
Affinity DataIC50: 107nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-9(Homo sapiens (Human))TBA
LigandPNGBDBM572144(US11447497, Example 1)copy SMILES
Affinity DataIC50: 122nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-3(Homo sapiens (Human))TBA
LigandPNGBDBM572144(US11447497, Example 1)copy SMILES
Affinity DataIC50: 132nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-8(Homo sapiens (Human))TBA
LigandPNGBDBM572144(US11447497, Example 1)copy SMILES
Affinity DataIC50: 132nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-3(Homo sapiens (Human))TBA
LigandPNGBDBM572147(US11447497, Example 4)copy SMILES
Affinity DataIC50: 200nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-8(Homo sapiens (Human))TBA
LigandPNGBDBM572146(US11447497, Example 3)copy SMILES
Affinity DataIC50: 396nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-3(Homo sapiens (Human))TBA
LigandPNGBDBM572146(US11447497, Example 3)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent
TargetCaspase-9(Homo sapiens (Human))TBA
LigandPNGBDBM572146(US11447497, Example 3)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Caspase-1 was diluted to 10 U/μl in assay buffer consisting of 50 mM HEPES, pH 7.4, 100 mM NaCl, 0.1% CHAPS, 1 mM EDTA, 10% glycerol and 10 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89W8US Patent