Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 10852
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533571(CHEMBL1618254 | US11459295, Compound R-Naproxen (1...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533576(CHEMBL4551048 | US11459295, Compound LM5752(+-) 4)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50533571(CHEMBL1618254 | US11459295, Compound R-Naproxen (1...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533577(CHEMBL1236131 | US11459295, Compound (S) 4b)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533572(CHEMBL4457933 | US11459295, Compound LM5753(+-) 3)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533569(CHEMBL4446810 | US11459295, Compound LM5751(+-) 2)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533574(CHEMBL4437071 | US11459295, Compound LM5750(+-) 8)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533570(CHEMBL4435662 | US11459295, Compound LM5750A 8b)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533571(CHEMBL1618254 | US11459295, Compound R-Naproxen (1...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM574725(US11459295, Compound DimethylNaproxen 9)copy SMILES
Affinity DataIC50: 270nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM54706(2-(6-methoxy-2-naphthalenyl)acetic acid | 2-(6-met...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM574720(US11459295, Compound LM5754(+-) 6)copy SMILES
Affinity DataIC50: 820nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50533571(CHEMBL1618254 | US11459295, Compound R-Naproxen (1...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM574719(US11459295, Compound LM5754(+-) 5)copy SMILES
Affinity DataIC50: 1.05E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM574725(US11459295, Compound DimethylNaproxen 9)copy SMILES
Affinity DataIC50: 1.32E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533577(CHEMBL1236131 | US11459295, Compound (S) 4b)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533576(CHEMBL4551048 | US11459295, Compound LM5752(+-) 4)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533570(CHEMBL4435662 | US11459295, Compound LM5750A 8b)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533569(CHEMBL4446810 | US11459295, Compound LM5751(+-) 2)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+3nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533572(CHEMBL4457933 | US11459295, Compound LM5753(+-) 3)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533571(CHEMBL1618254 | US11459295, Compound R-Naproxen (1...)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM574720(US11459295, Compound LM5754(+-) 6)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533573(CHEMBL4437291 | US11459295, Compound (R) 4a)copy SMILEScopy InChI
Affinity DataIC50: 4.35E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))TBA
LigandPNGBDBM50533575(CHEMBL4447175 | US11459295, Compound LM5885 (+-) 7)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM574719(US11459295, Compound LM5754(+-) 5)copy SMILES
Affinity DataIC50: 6.30E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533574(CHEMBL4437071 | US11459295, Compound LM5750(+-) 8)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM54706(2-(6-methoxy-2-naphthalenyl)acetic acid | 2-(6-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533575(CHEMBL4447175 | US11459295, Compound LM5885 (+-) 7)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 4.81E+4nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50533568(CHEMBL4466610 | US11459295, Compound LM5750B 8a)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The effect of the compounds on COX-1 activity was determined by a continuous colorimetric assay that monitored the oxidation of N, N, N, N-tetramethy...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0Z58US Patent