Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 11179
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191770(US10669227, Compound 7 | US11608309, Compound 7 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 1.70E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM445059(US10669227, Compound 5 | US11608309, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM597758(US11608309, Compound 8)copy SMILES
Affinity DataIC50: 4.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM191770(US10669227, Compound 7 | US11608309, Compound 7 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent