Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 1206
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10007(4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10013(4-[(6-Hydroxybenzofuran-2-yl)-[1,2,4]triazol-1-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10000((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10005(1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10001((4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10014(2-[(4-Nitrophenyl)-[1,2,4]triazol-1-ylmethyl]benzo...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10009(1-[(6-Methoxybenzofuran-2-yl)-p-tolylmethyl]-1H-1,...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10006(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10010(1-[(6-Methoxybenzofuran-2-yl)-(4-trifluoromethylph...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10003(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10002((6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)-3-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10015(2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10008(1-[(6-Methoxybenzofuran-2-yl)-(4-nitrophenyl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10011(1-[(4-ethylphenyl)(6-methoxy-1-benzofuran-2-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10012(2-[(4-Chlorophenyl)-[1,2,4]triazol-1-ylmethyl]benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed