Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 1259
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 102nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)copy SMILEScopy InChI
Affinity DataIC50: 119nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10479(A3A.2HCl | Bis-THA inhibitor 2 | CHEMBL378006 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 152nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 155nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 157nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 167nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 223nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 252nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10479(A3A.2HCl | Bis-THA inhibitor 2 | CHEMBL378006 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 254nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 329nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 711nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed