Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 1505
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11823(Azepane Derivative 4 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11823(Azepane Derivative 4 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11822((3R,4R)-3-(isonicotinoylamino)azepan-4-yl 4-(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11822((3R,4R)-3-(isonicotinoylamino)azepan-4-yl 4-(2-flu...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11824(Azepane Derivative 5 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11827(Azepane Derivative 8 | N-((3S,4S)-4-{(E)-2-[4-(2-f...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11824(Azepane Derivative 5 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 355nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11827(Azepane Derivative 8 | N-((3S,4S)-4-{(E)-2-[4-(2-f...)copy SMILEScopy InChI
Affinity DataIC50: 360nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11826(Azepane Derivative 7 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11826(Azepane Derivative 7 | N-((3R,4R)-4-{[4-(2-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics GmbH

LigandPNGBDBM11825(Azepane Derivative 6 | N-[(3S,4S)-4-({[4-(2-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics GmbH

LigandPNGBDBM11825(Azepane Derivative 6 | N-[(3S,4S)-4-({[4-(2-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1BNXPubMed