Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 1652
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7842(BAY 59-7939 Analog 17 | US8822458, 46)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12998(5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12997(5-Chloro-N-({(5S)-3-[3-fluoro-4-(3-oxomorpholin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12999(BAY 59-7939 Analog 14 | N-({(5S)-3-[3-Amino-4-(3-o...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7841(BAY 59-7939 Analog 18 | US8822458, 45 | US9359341,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13008(4-Amino-5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorphol...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13005(4-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13004(5-Bromo-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13010(5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12990(5-Chloro-N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12992(5-Chloro-N-{[(5S)-3-(3-fluoro-4-pyrrolidin-1-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7495(BAY 59-7939 Analog 7 | US8822458, 2)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12993(5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM12988(5-Chloro-N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 90nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13011(6-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7532(BAY 59-7939 Analog 10 | US8822458, 11)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13012(5-Chloro-N-methyl-N-({(5S)-2-oxo-3-[4-(3-oxomorpho...)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13009(2-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13006(3-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13013(5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM7632(BAY 59-7939 Analog 15 | US8822458, 36)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13007(2-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bayer HealthCare AG

LigandPNGBDBM13001(5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QR6PubMed