Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with all data for entry = 1661
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QVDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM11637((15S)-15-methyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QVDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10017((4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]m...)copy SMILEScopy InChI
Affinity DataIC50: 27nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10020((2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 137nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QVDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125QVDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)copy SMILEScopy InChI
Affinity DataKd:  45nMpH: 7.6 T: 2°CAssay Description:Dissociation constant of 667-coumate was measured for tight-binding inhibitors of CA II. The formation of the 4-nitrophenol was monitored at 348 nm f...More data for this Ligand-Target Pair