Compile Data Set for Download or QSAR
Found 42 Enz. Inhib. hit(s) with all data for entry = 1887
LigandPNGBDBM14797(Pyrazole carboxylic ester 20 | ethyl 1-(2-chloroph...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14798(Pyrazole carboxylic ester 21 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14798(Pyrazole carboxylic ester 21 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14797(Pyrazole carboxylic ester 20 | ethyl 1-(2-chloroph...)copy SMILEScopy InChI
Affinity DataIC50: 56nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14796(Pyrazole carboxylic ester 19 | ethyl 1-(4-aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14785(Pyrazole carboxylic ester 8 | ethyl 3,5-dimethyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14785(Pyrazole carboxylic ester 8 | ethyl 3,5-dimethyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 310nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14796(Pyrazole carboxylic ester 19 | ethyl 1-(4-aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14795(Pyrazole carboxylic ester 18 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 840nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14786(Pyrazole carboxylic ester 9 | ethyl 3-(4-chlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14795(Pyrazole carboxylic ester 18 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14786(Pyrazole carboxylic ester 9 | ethyl 3-(4-chlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14794(Pyrazole carboxylic ester 17 | ethyl 1-(4-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14790(Pyrazole carboxylic ester 13 | ethyl 1-(2,4-dinitr...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14794(Pyrazole carboxylic ester 17 | ethyl 1-(4-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14793(Pyrazole carboxylic ester 16 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14793(Pyrazole carboxylic ester 16 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14792(Pyrazole carboxylic ester 15 | ethyl 1-(4-tert-but...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14784(Pyrazole carboxylic ester 7 | cid_707658 | ethyl 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14790(Pyrazole carboxylic ester 13 | ethyl 1-(2,4-dinitr...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14787(Pyrazole carboxylic ester 10 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14787(Pyrazole carboxylic ester 10 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14784(Pyrazole carboxylic ester 7 | cid_707658 | ethyl 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14792(Pyrazole carboxylic ester 15 | ethyl 1-(4-tert-but...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14791(Pyrazole carboxylic ester 14 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14788(Pyrazole carboxylic ester 11 | ethyl 5-amino-1-{8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14791(Pyrazole carboxylic ester 14 | ethyl 3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14788(Pyrazole carboxylic ester 11 | ethyl 5-amino-1-{8-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14779(Pyrazole carboxylic ester 2 | ethyl 3,5-dimethyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14779(Pyrazole carboxylic ester 2 | ethyl 3,5-dimethyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14789(Pyrazole carboxylic ester 12 | ethyl 1-[3,5-bis(tr...)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14789(Pyrazole carboxylic ester 12 | ethyl 1-[3,5-bis(tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14781(Pyrazole carboxylic ester 4 | ethyl 3-amino-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14783(Pyrazole carboxylic ester 6 | methyl 3-methyl-5-(5...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14781(Pyrazole carboxylic ester 4 | ethyl 3-amino-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14780(Pyrazole carboxylic ester 3 | ethyl 3-methyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14778(3,5-dimethyl-1H-pyrazole-4-carboxylic acid | Pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14778(3,5-dimethyl-1H-pyrazole-4-carboxylic acid | Pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14780(Pyrazole carboxylic ester 3 | ethyl 3-methyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed
LigandPNGBDBM14783(Pyrazole carboxylic ester 6 | methyl 3-methyl-5-(5...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZCNPubMed