Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 2235
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)copy SMILEScopy InChI
Affinity DataKi:  200nM ΔG°:  -39.8kJ/mole IC50: 270nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)copy SMILEScopy InChI
Affinity DataKi:  280nM ΔG°:  -38.9kJ/mole IC50: 500nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)copy SMILEScopy InChI
Affinity DataKi:  300nM ΔG°:  -38.7kJ/mole IC50: 660nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)copy SMILEScopy InChI
Affinity DataKi:  420nM ΔG°:  -37.9kJ/mole IC50: 820nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nM ΔG°:  -33.5kJ/mole IC50: 4.20E+3nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nM ΔG°:  -31.2kJ/mole IC50: 1.30E+4nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  7.90E+4nM ΔG°:  -24.4kJ/mole IC50: 2.40E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18361((2R,3S,4R,5R,6R)-2-butyl-6-(hydroxymethyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nM ΔG°:  -23.5kJ/mole IC50: 1.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataKi:  1.16E+5nM ΔG°:  -23.4kJ/mole IC50: 2.70E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18366((2R,3R,5S,6R)-2,6-bis(hydroxymethyl)piperidine-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18363((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-octylpiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18361((2R,3S,4R,5R,6R)-2-butyl-6-(hydroxymethyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18360((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-propylpiperid...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+5nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18360((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-propylpiperid...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ649BPubMed