Compile Data Set for Download or QSAR
Found 20 Enz. Inhib. hit(s) with all data for entry = 2279
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)copy SMILEScopy InChI
Affinity DataIC50: 0.0190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.0250nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)copy SMILEScopy InChI
Affinity DataIC50: 0.0410nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.0480nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.0950nM EC50:  0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nM EC50:  0.280nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.760nM EC50:  0.300nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nM EC50:  3.5nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nM EC50:  0.380nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18866(3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18866(3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 21nM EC50:  150nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)copy SMILEScopy InChI
Affinity DataIC50: 25nM EC50:  11nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 130nM EC50:  190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed