Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for entry = 2289
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 22nM EC50:  32nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18886(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)-5-[(E)...)copy SMILEScopy InChI
Affinity DataIC50: 36nM EC50:  32nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 93nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18887(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...)copy SMILEScopy InChI
Affinity DataIC50: 460nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18883(3,5-dibromo-4-[4-hydroxy-3,5-bis(propan-2-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 910nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18883(3,5-dibromo-4-[4-hydroxy-3,5-bis(propan-2-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XDFPubMed