Compile Data Set for Download or QSAR
Found 189 Enz. Inhib. hit(s) with all data for entry = 2405
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199806(CHEMBL3944169 | US10913711, Compound 9a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  0.940nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  2.53nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199800(CHEMBL3979590 | US10913711, Compound 9g | US115550...)copy SMILEScopy InChI
Affinity DataKi:  2.54nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364421(US10913711, Compound 8b | US9862679, Compound 8b)copy SMILEScopy InChI
Affinity DataKi:  2.92nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364419(US10913711, Compound 8a | US9862679, Compound 8a)copy SMILEScopy InChI
Affinity DataKi:  3.17nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364429(US10913711, Compound 10g | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  3.43nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199854(CHEMBL3952924 | US10913711, Compound 7a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  3.58nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)copy SMILEScopy InChI
Affinity DataKi:  4.03nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199713(CHEMBL3965237 | US10913711, Compound 7b | US115550...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199795(CHEMBL3909363 | US10913711, Compound 9j | US115550...)copy SMILEScopy InChI
Affinity DataKi:  6.72nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)copy SMILEScopy InChI
Affinity DataKi:  16.7nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199854(CHEMBL3952924 | US10913711, Compound 7a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  16.8nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199854(CHEMBL3952924 | US10913711, Compound 7a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  19.9nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364419(US10913711, Compound 8a | US9862679, Compound 8a)copy SMILEScopy InChI
Affinity DataKi:  20.5nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364421(US10913711, Compound 8b | US9862679, Compound 8b)copy SMILEScopy InChI
Affinity DataKi:  25.9nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364406(US10913711, Compound 4c | US11555013, Compound 4c ...)copy SMILEScopy InChI
Affinity DataKi:  26.3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199713(CHEMBL3965237 | US10913711, Compound 7b | US115550...)copy SMILEScopy InChI
Affinity DataKi:  28.5nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364405(US10913711, Compound 4b | US11555013, Compound 4b ...)copy SMILEScopy InChI
Affinity DataKi:  29.9nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199800(CHEMBL3979590 | US10913711, Compound 9g | US115550...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199800(CHEMBL3979590 | US10913711, Compound 9g | US115550...)copy SMILEScopy InChI
Affinity DataKi:  31.8nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199795(CHEMBL3909363 | US10913711, Compound 9j | US115550...)copy SMILEScopy InChI
Affinity DataKi:  38.6nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364421(US10913711, Compound 8b | US9862679, Compound 8b)copy SMILEScopy InChI
Affinity DataKi:  42.4nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  47.2nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199806(CHEMBL3944169 | US10913711, Compound 9a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  49.6nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199713(CHEMBL3965237 | US10913711, Compound 7b | US115550...)copy SMILEScopy InChI
Affinity DataKi:  59.5nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199790(CHEMBL3916231 | US10913711, Compound 9d | US115550...)copy SMILEScopy InChI
Affinity DataKi:  84.7nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199806(CHEMBL3944169 | US10913711, Compound 9a | US115550...)copy SMILEScopy InChI
Affinity DataKi:  92.6nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199795(CHEMBL3909363 | US10913711, Compound 9j | US115550...)copy SMILEScopy InChI
Affinity DataKi:  95.4nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199792(CHEMBL3126735 | US10913711, Compound 4g | US115550...)copy SMILEScopy InChI
Affinity DataKi:  116nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364419(US10913711, Compound 8a | US9862679, Compound 8a)copy SMILEScopy InChI
Affinity DataKi:  116nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364404(US10913711, Compound 4a | US11555013, Compound 4a ...)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364411(US10913711, Compound 4i | US11555013, Compound 4i ...)copy SMILEScopy InChI
Affinity DataKi:  163nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  176nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)copy SMILEScopy InChI
Affinity DataKi:  194nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364414(US10913711, Compound 5c | US11555013, Compound 5c ...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199795(CHEMBL3909363 | US10913711, Compound 9j | US115550...)copy SMILEScopy InChI
Affinity DataKi:  213nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364404(US10913711, Compound 4a | US11555013, Compound 4a ...)copy SMILEScopy InChI
Affinity DataKi:  226nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364392(US9862679, Compound 2w)copy SMILEScopy InChI
Affinity DataKi:  228nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364393(US10913711, Compound 2x | US11555013, Compound 2x ...)copy SMILEScopy InChI
Affinity DataKi:  244nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364375(US10913711, Compound 2e | US11555013, Compound 2e ...)copy SMILEScopy InChI
Affinity DataKi:  277nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199713(CHEMBL3965237 | US10913711, Compound 7b | US115550...)copy SMILEScopy InChI
Affinity DataKi:  285nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364425(US10913711, Compound 10d | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  289nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364409(US10913711, Compound 4f | US11555013, Compound 4f ...)copy SMILEScopy InChI
Affinity DataKi:  297nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364405(US10913711, Compound 4b | US11555013, Compound 4b ...)copy SMILEScopy InChI
Affinity DataKi:  298nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364408(US10913711, Compound 4e | US11555013, Compound 4e ...)copy SMILEScopy InChI
Affinity DataKi:  315nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364429(US10913711, Compound 10g | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364423(US10913711, Compound 10j | US11555013, Compound 10...)copy SMILEScopy InChI
Affinity DataKi:  336nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199792(CHEMBL3126735 | US10913711, Compound 4g | US115550...)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM364395(US10913711, Compound 2z | US11555013, Compound 2z ...)copy SMILEScopy InChI
Affinity DataKi:  414nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
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