Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with all data for entry = 2654
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375232(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375233(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  23.9nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375234(3-chloro-5-(3-fluoropyridin-4-yl)-6-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375227(3-chloro-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataKi:  34.5nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375230(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375228(3-bromo-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  46.1nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375226(5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375231(3-chloro-6-(5-fluoropyridin-3-yl)-5-(3-fluoropyrid...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375228(3-bromo-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-2...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375227(3-chloro-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375232(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)...)copy SMILEScopy InChI
Affinity DataKi:  555nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375233(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375231(3-chloro-6-(5-fluoropyridin-3-yl)-5-(3-fluoropyrid...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375230(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)p...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375234(3-chloro-5-(3-fluoropyridin-4-yl)-6-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375226(5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)pyridin-2...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:The experiment of binding to MT3 sites was carried out on hamster brain membranes using [125I]2-iodomelatonin as radioligand in accordance with the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375227(3-chloro-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:The experiment of binding to MT3 sites was carried out on hamster brain membranes using [125I]2-iodomelatonin as radioligand in accordance with the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375228(3-bromo-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:The experiment of binding to MT3 sites was carried out on hamster brain membranes using [125I]2-iodomelatonin as radioligand in accordance with the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM375231(3-chloro-6-(5-fluoropyridin-3-yl)-5-(3-fluoropyrid...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The experiment of binding to MT3 sites was carried out on hamster brain membranes using [125I]2-iodomelatonin as radioligand in accordance with the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP48FVUS Patent