Compile Data Set for Download or QSAR
Found 460 Enz. Inhib. hit(s) with all data for entry = 2661
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375433(US9907800, Example A145)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375434(US10358436, Example A146 | US9907800, Example A146)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375434(US10358436, Example A146 | US9907800, Example A146)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50044670(CHEMBL3353359 | US10358436, Example A147 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375436(US10358436, Example A148 | US9907800, Example A148)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375437(US9907800, Example A149)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50044659(CHEMBL3353343 | US10358436, Example A150 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50044659(CHEMBL3353343 | US10358436, Example A150 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50073545(CHEMBL3408949 | US10358436, Example A151 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase A(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50073545(CHEMBL3408949 | US10358436, Example A151 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora A inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50073545(CHEMBL3408949 | US10358436, Example A151 | US99078...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375440(US10358436, Example A152 | US9907800, Example A152)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375443(US10358436, Example A154 | US9907800, Example A154)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375444(US9907800, Example A155)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375445(US10358436, Example A156 | US9907800, Example A156)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375446(US9907800, Example A157)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375447(US9907800, Example A158)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375447(US9907800, Example A158)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375449(US10358436, Example A159 | US9907800, Example A159)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375449(US10358436, Example A159 | US9907800, Example A159)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375450(US10358436, Example A160 | US9907800, Example A160)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375450(US10358436, Example A160 | US9907800, Example A160)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375451(US10358436, Example A161 | US9907800, Example A161)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375451(US10358436, Example A161 | US9907800, Example A161)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375452(US9907800, Example A162)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375452(US9907800, Example A162)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375453(US10358436, Example A163 | US9907800, Example A163)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375453(US10358436, Example A163 | US9907800, Example A163)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375454(US10358436, Example A164 | US9907800, Example A164)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375454(US10358436, Example A164 | US9907800, Example A164)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375455(US9907800, Example A165)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375455(US9907800, Example A165)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375456(US10358436, Example A84 | US9907800, Example A166)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375456(US10358436, Example A84 | US9907800, Example A166)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375457(US9907800, Example A167)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375457(US9907800, Example A167)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375458(US9907800, Example A168)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375458(US9907800, Example A168)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375459(US10358436, Example A169 | US9907800, Example A169)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375459(US10358436, Example A169 | US9907800, Example A169)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375461(US10358436, Example A171 | US9907800, Example A171)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase A(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375461(US10358436, Example A171 | US9907800, Example A171)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora A inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375461(US10358436, Example A171 | US9907800, Example A171)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375463(US10358436, Example A172 | US9907800, Example A172)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375463(US10358436, Example A172 | US9907800, Example A172)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375464(US10358436, Example A173 | US9907800, Example A173)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375464(US10358436, Example A173 | US9907800, Example A173)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375465(US10358436, Example A174 | US9907800, Example A174)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetAurora kinase B(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375465(US10358436, Example A174 | US9907800, Example A174)copy SMILES
Affinity DataIC50: 100nMAssay Description:Aurora B inhibition was determined using the Z-Lyte assay kit from Invitrogen. The assay was performed using the recommended manufacturer's instr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375466(US10358436, Example A175 | US9907800, Example A175)copy SMILES
Affinity DataIC50: 100nMAssay Description:PLK4 activity was measured using an indirect ELISA detection system. Dephosphorylated GST-PLK4 (4 nM) was incubated in the presence of 15 μM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD216WUS Patent
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