Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with all data for entry = 2949
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  5.90nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [H222S](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L54V](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  85nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L306A](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L308A](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MTWPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)copy SMILEScopy InChI
Affinity DataKi:  9.40E+4nM ΔG°:  -23.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair