Compile Data Set for Download or QSAR
Found 197 Enz. Inhib. hit(s) with all data for entry = 3004
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286987(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-((cyclopr...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286978(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286391(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287008(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287008(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287005(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287006(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287015((R)-8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286381(8-(2-((1-acryloylpiperidin-3-yl)oxy)ethyl)-6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287520(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM387926(1-(2-((1-acryloylazetidin-3-yl)(2-methoxyethyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287508(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287058((R)-8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287048(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287044(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286999(8-((1-((4-acryloylpiperazin-1-yl)methyl)cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286998(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286992(8-(2-((1-acryloylpiperidin-4-yl)oxy)ethyl)-6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287529(8-(2-((1-acryloylazetidin-3-yl)amino)ethyl)-6-(2,6...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287011(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287526((R)-8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)e...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287063(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287553((R)-8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287538(8-(2-((1-acryloylazetidin-3-yl)(2-methoxyethyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287520(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287077((S)-8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286986(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287005(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286388(8-(2-(4-acryloylpiperazin-1-yl)ethyl)-6-(2,6-dichl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286977(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287531(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287528(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287519(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287045(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287158(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287038(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287039(8-(3-(4-acryloylpiperazin-1-yl)propyl)-2-amino-6-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287535(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287508(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287538(8-(2-((1-acryloylazetidin-3-yl)(2-methoxyethyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287022((8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dic...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287517((S)-8-((1-(1-acryloylazetidin-3-yl)pyrrolidin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287001(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287559(8-(2-((1-acryloylpiperidin-4-yl)(methyl)amino)ethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287074(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-2-amino-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM387931((R)-N-(1-(3-(6-(2,6-dichloro-3,5-dimethoxyphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287555(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM286978(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:The cell-based effects of FGFR inhibitors were determined by measuring inhibition of FGFR-dependent cell line growth. The cell lines SNU-16 was used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM287041(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of FGFR family (FGFR1, FGFR2, FGFR3, FGFR4) kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX4DVZUS Patent
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