Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 3088
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27872(N-(diphenylmethyl)-3-hydroxy-4-sulfanylidene-4H-py...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27874(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27875(N-benzyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27869(3-hydroxy-N-[(4-phenylphenyl)methyl]-4-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27873(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27870(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27871(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27876(N-ethyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27859(3-hydroxy-N-[(4-phenylphenyl)methyl]-4-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27862(N-(diphenylmethyl)-3-hydroxy-4-sulfanylidene-4H-py...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27860(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 2.92E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27863(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 3.35E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27864(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 3.74E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27867(1-hydroxy-N-[(4-phenylphenyl)methyl]-6-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27861(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-sulfanylid...)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27866(N-ethyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 7.25E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27858(N-[(4-fluorophenyl)methyl]-1-hydroxy-6-oxo-1,6-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27868(N-[(4-fluorophenyl)methyl]-1-hydroxy-6-sulfanylide...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27856(N-ethyl-3-hydroxy-4-oxo-4H-pyran-2-carboxamide | h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27854(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-oxo-4H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27853(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-oxo-4H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27852(N-(diphenylmethyl)-3-hydroxy-4-oxo-4H-pyran-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27851(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-oxo-4H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27850(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-oxo-4H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27865(N-benzyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27855(N-benzyl-3-hydroxy-4-oxo-4H-pyran-2-carboxamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5CZVPubMed