Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 3103
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28030(2-aminopyridine analogue, 9 | N-{4-[(2-amino-3-chl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28028(2-aminopyridine analogue, 7 | N-{4-[(2-amino-3-eth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM24440(2-pyridone analogue, 2 | JMC521251 Compound 1 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28033(2-aminopyridine analogue, 12 | N-{4-[(2-amino-3-ch...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28026(2-aminopyridine analogue, 5 | N-(4-{[2-amino-3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28032(2-aminopyridine analogue, 11 | N-{4-[(2-amino-3-ch...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28027(2-aminopyridine analogue, 6 | N-(4-{[2-amino-3-(hy...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28029(2-aminopyridine analogue, 8 | N-(4-{[2-amino-3-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28025(2-aminopyridine analogue, 4 | N-(4-{[2-amino-3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28031(BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28023(N-{4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28024(2-aminopyridine analogue, 3 | N-[4-({2-amino-3-[(4...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20863MZPubMed