Compile Data Set for Download or QSAR
Found 99 Enz. Inhib. hit(s) with all data for entry = 3160
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)copy SMILEScopy InChI
Affinity DataIC50: 56nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 780nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28810(N-(3-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28814(N-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28823(N-(4-benzylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28820(N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28821(5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28816(5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28821(5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28818(N-(4-methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28836(N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28811(5-methyl-N-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28841(4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28822(5-methyl-N-(4-phenylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28814(N-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28833(N-(3,4-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28809(N-(3-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28834(N-(3,5-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28833(N-(3,4-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM24412(5-methyl-N-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28841(4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28812(5-methyl-N-[3-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28816(5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28828(5-methyl-N-(2,4,5-trifluorophenyl)-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28813(N-(4-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28836(N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28834(N-(3,5-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington at Seattle

LigandPNGBDBM28820(N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28832(N-(2-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington at Seattle

LigandPNGBDBM28827(5-methyl-N-(2,3,4-trifluorophenyl)-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
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