Compile Data Set for Download or QSAR
Found 71 Enz. Inhib. hit(s) with all data for entry = 3304
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31165(naphthyridinone analog.,19)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31153(3-hydroxyquinolin-2(1H)-one, 7)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31157(3-hydroxyquinolin-2(1H)-one, 11)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31154(3-hydroxyquinolin-2(1H)-one, 8)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31167(naphthyridinone analog.,21)copy SMILEScopy InChI
Affinity DataIC50: 128nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31155(3-hydroxyquinolin-2(1H)-one, 9)copy SMILEScopy InChI
Affinity DataIC50: 155nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)copy SMILEScopy InChI
Affinity DataIC50: 197nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)copy SMILEScopy InChI
Affinity DataIC50: 308nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 424nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31166(naphthyridinone analog.,20)copy SMILEScopy InChI
Affinity DataIC50: 784nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)copy SMILEScopy InChI
Affinity DataIC50: 855nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31165(naphthyridinone analog.,19)copy SMILEScopy InChI
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31171(3-hydroxyquinolin-2(1H)-one, 25)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)copy SMILEScopy InChI
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)copy SMILEScopy InChI
Affinity DataIC50: 4.62E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)copy SMILEScopy InChI
Affinity DataIC50: 7.64E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)copy SMILEScopy InChI
Affinity DataIC50: 8.47E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM31153(3-hydroxyquinolin-2(1H)-one, 7)copy SMILEScopy InChI
Affinity DataIC50: 8.72E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)copy SMILEScopy InChI
Affinity DataIC50: 8.88E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31163(3-hydroxyquinolin-2(1H)-one, 17)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)copy SMILEScopy InChI
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31162(3-hydroxyquinolin-2(1H)-one, 16)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31170(3-methoxyquinolin-2(1H)-one, 24)copy SMILEScopy InChI
Affinity DataIC50: 2.62E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31157(3-hydroxyquinolin-2(1H)-one, 11)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)copy SMILEScopy InChI
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-aspartic acid was linke...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ35HMPubMed
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