Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 333
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM719((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(2R)-2-[...)copy SMILEScopy InChI
Affinity DataKi:  0.0880nM ΔG°:  -59.7kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM718((4R)-3-[(2S,3S)-3-[(2-ethyl-3-hydroxyphenyl)formam...)copy SMILEScopy InChI
Affinity DataKi:  0.160nM ΔG°:  -58.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM717((4R)-N-[(2-chlorophenyl)methyl]-3-[(2S,3S)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.290nM ΔG°:  -56.6kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM580((4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylph...)copy SMILEScopy InChI
Affinity DataKi:  0.330nM ΔG°:  -56.3kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM579((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(2R)-2-[...)copy SMILEScopy InChI
Affinity DataKi:  0.740nM ΔG°:  -54.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM712((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2,6-dimethylphe...)copy SMILEScopy InChI
Affinity DataKi:  1.40nM ΔG°:  -52.6kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM715((4R)-N-tert-butyl-3-[(2S,3S)-3-[(2-ethyl-3-hydroxy...)copy SMILEScopy InChI
Affinity DataKi:  2.24nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM714((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  5.14nM ΔG°:  -49.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM716((4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylph...)copy SMILEScopy InChI
Affinity DataKi:  8.91nM ΔG°:  -47.8kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM708((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2,6-dimethylphe...)copy SMILEScopy InChI
Affinity DataKi:  21.7nM ΔG°:  -45.5kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM713((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  24.9nM ΔG°:  -45.1kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM710((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[2-(2-met...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM706((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[2-(3-met...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM705((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[2-(2-met...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM704((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-(2-phenox...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM709((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2-ethyl-6-methy...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM711((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2,6-diethylphen...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy Corporation

LigandPNGBDBM707((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[2-(4-met...)copy SMILEScopy InChI
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MP3PubMed