Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 3387
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.49nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 1.91nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.35nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.43nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 239nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 767nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 768nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 901nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 1.17E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.72E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 6.16E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent