Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 3427
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33410(CHEMBL16755 | N-hydroxyisoquinolinedione, 2)copy SMILEScopy InChI
Affinity DataIC50: 135nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33419(pyrimidinol carboxylic acid, 11)copy SMILEScopy InChI
Affinity DataIC50: 175nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33411(β-Thujaplicinol | hydroxytropolone, 3)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33418(pyrimidinol carboxylic acid, 10)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33417(pyrimidinol carboxylic acid, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33412(CHEMBL183852 | N-hydroxy quinazolinedione, 4 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33409(alpha, gamma-diketo acid, 1)copy SMILEScopy InChI
Affinity DataIC50: 9.85E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33416(pyrimidinol carboxylic acid, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)copy SMILEScopy InChI
Affinity DataIC50: 2.32E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33419(pyrimidinol carboxylic acid, 11)copy SMILEScopy InChI
Affinity DataIC50: 4.85E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences Inc.

LigandPNGBDBM33420(pyrimidinol carboxylic acid, 12)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33418(pyrimidinol carboxylic acid, 10)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33416(pyrimidinol carboxylic acid, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33417(pyrimidinol carboxylic acid, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed
TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences Inc.

LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM78F2PubMed