Compile Data Set for Download or QSAR
Found 44 Enz. Inhib. hit(s) with all data for entry = 3507
TargetHistone deacetylase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 0.958nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 1.05nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 9 [604-1066](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 17.7nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US PatentDrugBank
TargetHistone deacetylase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 20.7nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 23.9nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 27.1nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-489](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 7 [518-592](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 32.4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 65.7nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 4 [627-1085](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 293nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-489](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 435nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 472nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 508nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 597nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 604nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 683nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-489](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 9 [604-1066](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 7 [518-592](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 2.84E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 4 [627-1085](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 3.53E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 4.26E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 7 [518-592](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 4.29E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM402284((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 4 [627-1085](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 5.78E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 9 [604-1066](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 6.93E+3nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-489](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 9 [604-1066](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 7 [518-592](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent
TargetHistone deacetylase 4 [627-1085](Homo sapiens (Human))
Istanbul University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+4nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5QJ0US Patent