Compile Data Set for Download or QSAR
Found 140 Enz. Inhib. hit(s) with all data for entry = 363
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1105((4R,5R,6R)-Tetrahydro-1,3-bis[(3-(N-hydroxycarboxi...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM50404011(CHEMBL36900)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1150((4R,5R,6R)-Tetrahydro-1-(3-aminophenyl-methyl)-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1104((4R,5R,6R)-Tetrahydro-1,3-bis[(3-(N-hydroxycarboxi...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nM ΔG°:  -63.5kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM50404007(CHEMBL116517)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM164((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(1H-indazol-5...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1150((4R,5R,6R)-Tetrahydro-1-(3-aminophenyl-methyl)-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM50065089((4R,5R,6R)-Tetrahydro-1,3-bis[(3-benzamide oxime)-...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM182((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.0270nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1110((4R,5R,6R)-1,3-bis[(3-amino-1H-indazol-5-yl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nM ΔG°:  -62.5kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1110((4R,5R,6R)-1,3-bis[(3-amino-1H-indazol-5-yl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1113((4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(3-(thiazo...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1113((4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(3-(thiazo...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nM ΔG°:  -62.5kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1149((4R,5R,6R)-Tetrahydro-1-(3-aminophenyl-methyl)-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM172((4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis[(3-acetylphenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1106((4R,5R,6R)-Tetrahydro-1,3-bis[(3-(N-hydroxycarboxi...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nM ΔG°:  -60.7kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM50404006(CHEMBL366576)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1149((4R,5R,6R)-Tetrahydro-1-(3-aminophenyl-methyl)-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1108((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(1H-indazol-6...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1108((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(1H-indazol-6...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nM ΔG°:  -60.7kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1144((4R,5R,6R)-1-[(3-aminophenyl)methyl]-4-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1112((4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(3-(5-meth...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1112((4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(3-(5-meth...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1144((4R,5R,6R)-1-[(3-aminophenyl)methyl]-4-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1080((4R,5R,6R)-Tetrahydro-1,3-bis[(3-benzamido)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1109((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[(3-methyl-1H...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1148((4R,5R,6R)-1-[(3-amino-1H-indazol-5-yl)methyl]-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1145((4R,5R,6R)-1-[(3-aminophenyl)methyl]-6-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1107((4R,5R,6R)-4-benzyl-5-hydroxy-6-(2-phenylethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1109((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[(3-methyl-1H...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1107((4R,5R,6R)-4-benzyl-5-hydroxy-6-(2-phenylethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1145((4R,5R,6R)-1-[(3-aminophenyl)methyl]-6-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1148((4R,5R,6R)-1-[(3-amino-1H-indazol-5-yl)methyl]-3-[...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1726((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[(...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1146((4R,5R,6R)-1-[(3-aminophenyl)methyl]-6-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1146((4R,5R,6R)-1-[(3-aminophenyl)methyl]-6-benzyl-5-hy...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM50408711(CHEMBL277389)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1730((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1102((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1102((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1131((4R,5R,6R)-Tetrahydro-1-(3-(N-hydroxycarboximidami...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1131((4R,5R,6R)-Tetrahydro-1-(3-(N-hydroxycarboximidami...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1090((4R,5R,6R)-1,3-bis[(3-amino-4-fluorophenyl)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1143((4R,5R,6R)-1-[(3-amino-1H-indazol-5-yl)methyl]-3,6...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1143((4R,5R,6R)-1-[(3-amino-1H-indazol-5-yl)methyl]-3,6...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM151((4R,5S,6S,7R)-1,3-bis[(3-aminophenyl)methyl]-4,7-d...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1089((4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[(3-hydroxyph...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1101((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1101((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxamidophenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.310nM ΔG°:  -56.5kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
DuPont Pharmaceuticals Company

LigandPNGBDBM1133((4R,5R,6R)-1-[(3-amino-1H-indazol-5-yl)methyl]-6-b...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28050S9PubMed
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