Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50000025
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000438(5-(4-Dimethylamino-phenylcarbamoyl)-pyridine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000430(5-(4-Ethoxy-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000437(5-p-Tolylcarbamoyl-pyridine-2-carboxylic acid; ace...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000417(5-(2-Fluoro-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000429(5-(4-Ethoxy-benzoylamino)-pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000420(5-(4-Dimethylamino-benzoylamino)-pyridine-2-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000433(5-(2-Methoxy-phenylcarbamoyl)-pyridine-2-carboxyli...)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000424(5-(4-Fluoro-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000441(5-(2-Chloro-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000434(5-(4-Methyl-benzoylamino)-pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000436(5-(2,4-Dimethoxy-phenylcarbamoyl)-pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000432(5-(4-Chloro-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000442(5-(4-Methoxy-phenylcarbamoyl)-pyridine-2-carboxyli...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000435(5-(4-Chloro-benzoylamino)-pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000428(5-Benzoylamino-pyridine-2-carboxylic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000421(5-(3,4,5-Trimethoxy-phenylcarbamoyl)-pyridine-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000440(5-Phenylcarbamoyl-pyridine-2-carboxylic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000423(5-(4-Fluoro-benzylamino)-pyridine-2-carboxylic aci...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000419(5-(3-Chloro-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000418(5-(2-Ethoxy-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000427(5-(2-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000431(5-Benzyloxy-pyridine-2-carboxylic acid | CHEMBL166...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000422(5-(4-Nitro-phenylcarbamoyl)-pyridine-2-carboxylic ...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000426(5-(4-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000423(5-(4-Fluoro-benzylamino)-pyridine-2-carboxylic aci...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated for inhibition of Prolyl 4-hydroxylase activity in cultured embryonic chick tendon cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
ICI Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000425(5-[2-(4-Chloro-phenyl)-vinyl]-pyridine-2-carboxyli...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed