Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50000321
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of Progesterone 21-hydroxylase cytochrome P450 21More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 11B1, mitochondrial(Bos taurus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of Corticoid 11-beta-hydroxylase cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 11B1, mitochondrial(Bos taurus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 11B1, mitochondrial(Bos taurus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 247nMAssay Description:Inhibition of Corticoid 11-beta-hydroxylase cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2A2(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 369nMAssay Description:Inhibition of cytochrome P450 progesterone 15-alpha hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2A2(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 543nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 546nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of progesterone 6-beta-hydroxylase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 11B1, mitochondrial(Bos taurus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 608nMAssay Description:Inhibition of Corticoid 11-beta-hydroxylase cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2A2(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 728nMAssay Description:Inhibition of cytochrome P450 progesterone 15-alpha hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 786nMAssay Description:Inhibition of Corticoid 11-beta-hydroxylase cytochrome P450More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 897nMAssay Description:Inhibition of progesterone 6-beta-hydroxylase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2A2(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of cytochrome P450 progesterone 15-alpha hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of progesterone 6-beta-hydroxylase in rat hepatic microsomesMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetAromatase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of Progesterone 21-hydroxylase cytochrome P450 21More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.57E+3nMAssay Description:Inhibition of Progesterone 21-hydroxylase cytochrome P450 21More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibition of Progesterone 21-hydroxylase cytochrome P450 21More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of cytochrome P450 progesterone 2-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of cytochrome P450 progesterone 2-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of cytochrome P450 progesterone 2-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetAromatase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetAromatase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 8.41E+4nMAssay Description:Inhibition of cytochrome P450 progesterone 15-alpha hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of cytochrome P450 progesterone 2-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetAromatase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of progesterone 6-beta-hydroxylase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed