Compile Data Set for Download or QSAR
Found 63 Enz. Inhib. hit(s) with all data for entry = 50000446
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250493(CHEMBL4068445)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250492(CHEMBL4097304)copy SMILEScopy InChI
Affinity DataKi:  0.0980nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250501(CHEMBL4078562)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250490(CHEMBL4087166)copy SMILEScopy InChI
Affinity DataKi:  0.490nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349975((S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-...)copy SMILEScopy InChI
Affinity DataKi:  0.710nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250494(CHEMBL4089581)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250495(CHEMBL4081710)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250491(CHEMBL4105006)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250512(CHEMBL4059788)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250511(CHEMBL4079281)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM161055(US9108951, 10 | US9394276, 10 | US9725435, 10)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250489(CHEMBL4090783)copy SMILEScopy InChI
Affinity DataKi: <5nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349974((E)-4-(2-(3-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)a...)copy SMILEScopy InChI
Affinity DataKi: <5nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349979((E)-4-(2-(3-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)a...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250496(CHEMBL4074535)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250485(CHEMBL4063912)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM161052(US9108951, 3 | US9394276, 3 | US9725435, 3)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250482(CHEMBL4085488)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250500(CHEMBL4082994)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250499(CHEMBL4063157)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250472(CHEMBL4070736)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250481(CHEMBL4084801)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM170408(US9079929, 34)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250513(CHEMBL4103298)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250486(CHEMBL4072510)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250488(CHEMBL4100970)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250479(CHEMBL4078868)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250480(CHEMBL4096900)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250475(CHEMBL4077773)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250477(CHEMBL4081328)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250459(CHEMBL4089256)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250473(CHEMBL4097854)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM161066(US9108951, 86 | US9394276, 86 | US9725435, 86)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250463(CHEMBL4100305)copy SMILEScopy InChI
Affinity DataKi:  57nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250498(CHEMBL4089196)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250460(CHEMBL4069553)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250464(CHEMBL4082288)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250471(CHEMBL4081335)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250474(CHEMBL4101257)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250514(CHEMBL4060887)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250497(CHEMBL4070724)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250457(CHEMBL4099224)copy SMILEScopy InChI
Affinity DataKi:  270nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250461(CHEMBL4095863)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250516(CHEMBL4077834)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM349975((S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Inhibition of human plasma kallikrein using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250476(CHEMBL4105579)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250456(CHEMBL4081202)copy SMILEScopy InChI
Affinity DataKi:  640nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250462(CHEMBL4062109)copy SMILEScopy InChI
Affinity DataKi:  870nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM161060(US9108951, 42 | US9394276, 42 | US9725435, 42)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50250458(CHEMBL4080257)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
Displayed 1 to 50 (of 63 total ) | Next | Last >>
Jump to: