Compile Data Set for Download or QSAR
Found 216 Enz. Inhib. hit(s) with all data for entry = 50000457
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrate in presence of NAPDHMore data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50103568(CHEMBL3335794)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50103568(CHEMBL3335794)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250689(CHEMBL4069726 | US10961200, Compound 47 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250691(CHEMBL4062709 | US10961200, Compound 166 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250641(CHEMBL4069450 | US10961200, Compound 97 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250676(CHEMBL4076958 | US10961200, Compound 48 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250676(CHEMBL4076958 | US10961200, Compound 48 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250676(CHEMBL4076958 | US10961200, Compound 48 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250675(CHEMBL4069796 | US10961200, Compound 41 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250675(CHEMBL4069796 | US10961200, Compound 41 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250695(CHEMBL4103659 | US10961200, Compound 63 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250665(CHEMBL4076264 | US10961200, Compound 425 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250675(CHEMBL4069796 | US10961200, Compound 41 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250676(CHEMBL4076958 | US10961200, Compound 48 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250681(CHEMBL4096677)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250654(CHEMBL4082867 | US10961200, Compound 187 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250654(CHEMBL4082867 | US10961200, Compound 187 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250654(CHEMBL4082867 | US10961200, Compound 187 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250642(CHEMBL4095904 | US10961200, Compound 95 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250690(CHEMBL4067976 | US10961200, Compound 50 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250654(CHEMBL4082867 | US10961200, Compound 187 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250699(CHEMBL4098516 | US10961200, Compound 33 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250675(CHEMBL4069796 | US10961200, Compound 41 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250669(CHEMBL4081640)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
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