Compile Data Set for Download or QSAR
Found 72 Enz. Inhib. hit(s) with all data for entry = 50000955
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Competitive inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266041(CHEMBL4070212)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266064(CHEMBL4104310)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of rat KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50131810(CHEMBL3634602)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266097(CHEMBL4062730)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266065(CHEMBL4084414)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266002(CHEMBL4081917)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266116(CHEMBL4077245)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266033(CHEMBL4070050)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266001(CHEMBL4071379)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266040(CHEMBL4099913)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266002(CHEMBL4081917)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266088(CHEMBL4086792)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Pseudomonas fluorescens)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266041(CHEMBL4070212)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Pseudomonas fluorescens KMO expressed in Escherichia coli using kynurenine as substrate measured after 1 hr by RapidFire high-throughpu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266034(CHEMBL4075380)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266001(CHEMBL4071379)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266121(CHEMBL4099039)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237995(CHEMBL4096688)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266038(CHEMBL4074106)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266040(CHEMBL4099913)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266096(CHEMBL4092169)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266069(CHEMBL4075695)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266104(CHEMBL4085877)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266035(CHEMBL4071903)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266087(CHEMBL4064339)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237991(CHEMBL4071986)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266067(CHEMBL4072423)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237991(CHEMBL4071986)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266036(CHEMBL4092205)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266121(CHEMBL4099039)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266036(CHEMBL4092205)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237994(CHEMBL4082723)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266003(CHEMBL4091152)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KMO in human primary hepatocytes using kynurenine as substrate measured after overnight incubation by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237992(CHEMBL4061355)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266004(CHEMBL4063199)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50131812(CHEMBL3634600)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266104(CHEMBL4085877)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266068(CHEMBL4059840)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266116(CHEMBL4077245)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266065(CHEMBL4084414)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266014(CHEMBL4068504)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266087(CHEMBL4064339)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266038(CHEMBL4074106)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50131813(CHEMBL3634599)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of KMO in human primary hepatocytes using kynurenine as substrate measured after overnight incubation by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50266088(CHEMBL4086792)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50131813(CHEMBL3634599)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26112SBPubMed
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