Compile Data Set for Download or QSAR
Found 30 Enz. Inhib. hit(s) with all data for entry = 50001018
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011932(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011937(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011933(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011932(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011933(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)copy SMILEScopy InChI
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011933(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)copy SMILEScopy InChI
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)copy SMILEScopy InChI
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011932(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011937(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50011937(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z14G6PubMed