Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for entry = 50001188
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1GWQPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50271601(CHEMBL4130209 | US10543199, Compound 18)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1GWQPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human ALR2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human ALR2More data for this Ligand-Target Pair