Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50001407
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)copy SMILEScopy InChI
Affinity DataIC50: 218nMAssay Description:Tested in vitro for histamine H3 receptor mediate inhibition of neurogenic contractions in guinea pig isolated ileum assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278276(CHEMBL4176702)copy SMILEScopy InChI
Affinity DataIC50: 314nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)copy SMILEScopy InChI
Affinity DataIC50: 413nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278276(CHEMBL4176702)copy SMILEScopy InChI
Affinity DataIC50: 491nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278277(CHEMBL4169910 | US11352322, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278277(CHEMBL4169910 | US11352322, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278276(CHEMBL4176702)copy SMILEScopy InChI
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278277(CHEMBL4169910 | US11352322, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)copy SMILEScopy InChI
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278276(CHEMBL4176702)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278277(CHEMBL4169910 | US11352322, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278273(CHEMBL4173338)copy SMILEScopy InChI
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278274(CHEMBL4166084)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278276(CHEMBL4176702)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278275(CHEMBL4162637)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50278277(CHEMBL4169910 | US11352322, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6NK6PubMed