Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50001449
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280395(CHEMBL4171480)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human GST-tagged EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280396(CHEMBL4160863)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPAC2 expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine nucleotide exchange ac...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280394(CHEMBL4168137)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280395(CHEMBL4171480)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPAC2 expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine nucleotide exchange ac...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280396(CHEMBL4160863)copy SMILEScopy InChI
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
Institute for Research in Cancer and Allied Diseases

Curated by ChEMBL
LigandPNGBDBM50280397(CHEMBL4175985)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged EPAC1 (149 to 881 residues) expressed in Escherichia coli Rosetta 2(DE3) assessed as reduction in guanine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4Z83PubMed