Compile Data Set for Download or QSAR
Found 50 Enz. Inhib. hit(s) with all data for entry = 50001466
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015711(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015714(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015712(5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015709(5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015717(5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015718(5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM31023(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015709(5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015717(5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015714(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015711(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015718(5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015712(5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM31023(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 2 receptor of rat anterior cortex using [3H]ketanserin as the radiolig...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataEC50:  56nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataEC50:  26nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1D receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1A receptor of guinea pig hippocampusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1A receptor of guinea pig hippocampusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(GUINEA PIG)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1D receptor of guinea pig substantia nigraMore data for this Ligand-Target Pair