Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 50001530
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283464(CHEMBL4162764)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283462(CHEMBL4176393)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283465(CHEMBL4168783)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283444(CHEMBL4173010)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283442(CHEMBL4172770)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283446(CHEMBL4169616)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283461(CHEMBL4164548)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283463(CHEMBL4176581)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283447(CHEMBL4168400)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283459(CHEMBL4159400)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283468(CHEMBL4165785)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283460(CHEMBL4177474)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283467(CHEMBL4162337)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283466(CHEMBL4176640)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-II(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetATP-dependent RNA helicase DHX29(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetATP-dependent RNA helicase DHX29(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetATP-dependent RNA helicase DHX29(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-II(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal full length His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-II(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7KT3PubMed