Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for entry = 50001586
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50286290(CHEMBL4174314)copy SMILEScopy InChI
Affinity DataIC50: 0.497nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75JVWPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50286289(CHEMBL4166054)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75JVWPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50286288(CHEMBL4159636)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75JVWPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75JVWPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75JVWPubMed