Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for entry = 50001748
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365388(CHEMBL4165362)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM309129((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM308813((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50366117(CHEMBL4176089)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365371(CHEMBL4168242)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50366116(CHEMBL4174148)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365378(CHEMBL4160468)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM309315((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365372(CHEMBL4176431)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM308815((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365385(CHEMBL4166232)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM308876(N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365377(CHEMBL4161927)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM308854(N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365375(CHEMBL4162798)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365369(CHEMBL4172970)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365370(CHEMBL4170790)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50366249(CHEMBL4171068)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365380(CHEMBL4172573)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365387(CHEMBL4175269)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365382(CHEMBL4172641)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365381(CHEMBL4177049)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365373(CHEMBL4169188)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365368(CHEMBL4173675)copy SMILEScopy InChI
Affinity DataKi:  97nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50366115(CHEMBL4160146)copy SMILEScopy InChI
Affinity DataKi:  118nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365374(CHEMBL4164756)copy SMILEScopy InChI
Affinity DataKi:  198nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365383(CHEMBL4162199)copy SMILEScopy InChI
Affinity DataKi:  199nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365379(CHEMBL4165757)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365376(CHEMBL4174212)copy SMILEScopy InChI
Affinity DataKi:  766nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365386(CHEMBL4167394)copy SMILEScopy InChI
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365389(CHEMBL4169148)copy SMILEScopy InChI
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50365384(CHEMBL4162376)copy SMILEScopy InChI
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed